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ref: Kato-2006.01 tags: bioactive neural probes flexible parylene japan Kato microspheres date: 01-28-2013 03:57 gmt revision:1 [0] [head]

PMID-17946847[0] Preliminary study of multichannel flexible neural probes coated with hybrid biodegradable polymer.

  • Conference proceedings. a little light.
  • :-)
  • probes made of parylene-C

____References____

[0] Kato Y, Saito I, Hoshino T, Suzuki T, Mabuchi K, Preliminary study of multichannel flexible neural probes coated with hybrid biodegradable polymer.Conf Proc IEEE Eng Med Biol Soc 1no Issue 660-3 (2006)

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ref: Menei-1994.09 tags: microspheres beads polycaprolactone biocompatible drug delivery histology date: 01-27-2013 20:54 gmt revision:3 [2] [1] [0] [head]

PMID-7814435 Fate and biocompatibility of three types of microspheres implanted into the brain.

  • microspheres ( 24μm 24 \mu m ) appear to be engulfed or surrounded by histocytic cells.
  • poly(e-caprolactone), which is supposed to be biodegradable, did not dissolve in the brain. The polymer is hydrophobic.
  • 20um spheres could be engulfed by macrophages; their microspheres were too large, and were encapsulated in a thin coallagen layer and astrocytic process.
  • no scale bars - annoying - but we can estimate the size of the coating to be about the same size as the beads themselves.