[0] Fetz EE, Baker MA, Operantly conditioned patterns on precentral unit activity and correlated responses in adjacent cells and contralateral muscles.J Neurophysiol 36:2, 179-204 (1973 Mar)


{341} revision 2 modified: 01-07-2012 19:34 gmt

PMID-4196269[0] Operantly conditioned patterns on precentral unit activity and correlated responses in adjacent cells and contralateral muscles

  • Looked at an operant task through the opposite direction: as a means for looking at reaction time, and muscle responses to trained bursts of activity.
  • recorded from precentral gyrus cells in leg and arm representation.
    • isonel coated tungsten microwires, with great apparent waveform records.
  • also recorded EMG, nylon-insuldated stainless-steel wire, led subcutaneuosly to the head connector.
  • references an even older study concerning the operant conditioning of neural activity in rats by Olds.
  • really simple technology - RC filter to estimate the rate; reward high rate; resets on reward.
    • the evoked operant bursts are undoubtably due to training.
  • looks like it was easy for the monkeys to increase the firing rate of their cortical cells (of course, I'm just skimming the article..)
  • 233 precentral units.
    • which they did some preliminary somatotopic mapping of.
  • neighboring cells mirrored the firing rate changes (logical as they share the local circuitry)
  • in a few sessions the operant bursts were not associated with movements.
  • Could individually condition cells when they happened to record 2 units on the same electrode.

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