PMID-20404313[0] Spinal cord stimulation failed to relieve akinesia or restore locomotion in Parkinson disease.
- motivated by [1]
- Implanted two PD patients with commercial DBS stimulators and electrodes; observed no therapeutic effect.
- Electric field was axial rather than transverse, hence likely did not activate the same way or same ammount as in the Nicolelis study.
- Not sure if anyone has tried with other eletrodes... spinal cord stimulation would be great for inductive powering.
____References____
[0] Thevathasan W, Mazzone P, Jha A, Djamshidian A, Dileone M, Di Lazzaro V, Brown P, Spinal cord stimulation failed to relieve akinesia or restore locomotion in Parkinson disease.Neurology 74:16, 1325-7 (2010 Apr 20) |
[1] Fuentes R, Petersson P, Siesser WB, Caron MG, Nicolelis MA, Spinal cord stimulation restores locomotion in animal models of Parkinson's disease.Science 323:5921, 1578-82 (2009 Mar 20) |
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