PMID-7284825[0] Connections of the subthalamic nucleus in the monkey.
- STN projects to both segments of the globus pallidus in a laminar and organized fashion.
- most fibers projected to the lateral pallidal segment (aka GPe).
- also projected to specific thalamic nuclei (VAmc, VLm, DMpl).
- the major projection of PPN is to SN.
- striatum projects to the substantia nigra pars reticulata (SNr). interesting.
- see also: PMID-1707079[1]
- "Anterograde transport in fibers and terminal fields surrounded retrogradely labeled cells in the LPS (GPe), suggesting a reciprocal relationship [to the STN]"
- These data suggest that the STN receives its major subcortical input from cell of the LPS (GPe) arranged in arrays which have a rostrocaudal organization.
- No cells of the MPS (GPi) or SN project to the STN.
- The output of the STN is to both segments of the GP and SNpr.
- Major subcortical projections to PPN arise from the MPS (GPi) and SNpr (output of the BG) , but afferents also arise from other sources.
- The major projection of PPN is to SN.
- HRP injected into PPN produced profuse retrograde transport in cells of the MPS and SNpr and distinct label in a few cells of the zona incerta and STN.
____References____
[0] Carpenter MB, Carleton SC, Keller JT, Conte P, Connections of the subthalamic nucleus in the monkey.Brain Res 224:1, 1-29 (1981 Nov 9) |
[1] Carpenter MB, Jayaraman A, Subthalamic nucleus of the monkey: connections and immunocytochemical features of afferents.J Hirnforsch 31:5, 653-68 (1990) |
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