A contact lens with embedded sensor for monitoring tear glucose level
- PMID-21257302
- Metal stack: Ti 10nM / Pd 10nM / Pt 100nm.
- on a 100um thick PET film.
- A 30 µL glucose oxidase solution (10 mg/mL) was dropped onto the sensor area.
- Then the sensor was suspended vertically above a titanium isopropoxide solution in a sealed dish for 6 h to create a GOD/titania sol-gel membrane, just as reported (Yu et al., 2003).
- After forming the sol-gel membrane, a 30 µL aliquot of Nafion® solution was dropped onto the same area of the sensor, and allowed to dry in air for about 20 min.
- Yet, the interference rejection from Nafion is imperfect; at 100uM concentrations, glucose is indistinguishable from ascorbic acid + lactate + urea.
- Sensor drifts to 55% original performance after 4 days: figure 6
- sensor was stored in a buffer @ 4C.
- Probably OK for contact lenses, though.
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